Do not add registration marks in Signlab! They are added in VPM5 instead.
Make your Sign.
Make objects that you want cut, contour cut objects by selecting them, and then click on Cut/Contour cut.
In VPM5, install your cutter.
Go to Queue/Properties/Cutter/Registration Marks.
Change the regmark system from Disabled, to the one mathching the cutter settings
Cutting with Registration Marks
Ensure that the cutter and VPM are set for the same mark types, number of marks (4 pts recommended), size (0.50 default).
When sending to cut from VPM, you will be prompted to move the knife near the registration mark.
Using the cutter arrows move the knife to a bit down and the left of the first reg mark (it is the closest to you on the right)
Press the Origin button to set the new 0,0 point.
Send to Cut from VPM
All Reg Marks settings in VPM are here:
Queue menu > Properties > Cutter > Registration Marks
When cutting long jobs, you should use the Segmented registrations marks.